Autophosphorylation of receptor tyrosine kinases depends on which of the following?

Question

Quizplus · Accepted Answer

Autophosphorylation of receptor tyrosine kinases requires all of the above factors. Dimerization of the receptor brings the kinase domains into proximity for phosphorylation, ATP provides the phosphate groups used for phosphorylation, ligand binding can induce conformational changes that promote autophosphorylation, and transmission of conformational changes through the membrane can also initiate autophosphorylation.

Autophosphorylation of Receptor Tyrosine Kinases Depends on Which of the Following