Mutations in which of the following are not part of the progression from normal to cancerous cells in colorectal cancer?
A)Abl involved in cellular signaling
B)KRAS and BRAF kinases involved in cellular signaling
C)PI3K and PTEN involved in cellular signaling
D)MMR involved in DNA repair
E)CDC4 involved in ubiquitination

Question

Quizplus · Accepted Answer

Abl is not typically associated with the progression of colorectal cancer, whereas KRAS, BRAF, PI3K, PTEN, MMR, and CDC4 are more commonly implicated in the disease's development.

Mutations in Which of the Following Are Not Part of the Progression