Typical fatty acids cannot be converted to glucose because ________.

Question

Quizplus · Accepted Answer

Fatty acids are broken down into two-carbon units and converted to acetyl-CoA, which cannot be converted to glucose through gluconeogenesis. This is because of the irreversible step in the pyruvate dehydrogenase complex that converts pyruvate to acetyl-CoA. The only exception is the fatty acid, odd-chain fatty acids, which are first converted to propionyl-CoA and can eventually enter the gluconeogenesis pathway.

Typical Fatty Acids Cannot Be Converted to Glucose Because ________