Which of the following typically occurs in HER2+ breast cancer cells in response to treatment with Herceptin?
A) Levels of phosphorylated Akt decrease.
B) Transphosphorylation of the HER3 receptor by HER2 tyrosine kinase is reduced.
C) Phosphorylation of PRAS is reduced.
D) Cells become more sensitive to radiation and chemotherapy.
E) All of the above.
Correct Answer:
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A)All
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