In a mouse model of breast carcinoma in which mouse mammary carcinoma cells were injected orthotopically into the mouse mammary tissue,cells in which the transcription factor Twist was knocked down by siRNA
A)Formed primary tumors at least as rapidly as control cells.
B)Took twice as long as control cells to form tumors.
C)Had reduced metastases to the lungs.
D)A and C.
E)All of the above.

Question

Quizplus · Accepted Answer

The passage states that cells with Twist knocked down formed primary tumors at least as rapidly as control cells, so option A is incorrect. However, it also states that cells with Twist knocked down had reduced metastases to the lungs, so option C is correct. Therefore, the correct answer is D) A and C.

In a Mouse Model of Breast Carcinoma in Which Mouse