Which of the following statements is FALSE?
A) Most carcinomas depend upon stromal cells for support.
B) Tumors growing in the ascites and pleural fluid require stromal cells for structural support.
C) Many genes activated during stromal development in tumors are also activated during the wound-healing response.
D) The growth of large tumors is dependent upon the genesis of blood vessels to supply nutrients and oxygen to the cells.
E) None of the above.
Correct Answer:
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Q1: Myofibroblasts
A)Secrete matrix metalloproteinases MMPs).
B)Have serine in their
Q2: Angiogenesis inhibitors are an attractive anti-cancer agent
Q3: Epithelial cells undergoing an epithelial-to-mesenchymal transition EMT)will
A)Migrate
Q4: Many anti-cancer drugs are often first tested
Q5: Which of the following is NOT an
Q7: VEGF is involved in
A)Monocytic migration.
B)Hematopoiesis.
C)Capillary permeability.
D)Angiogenesis.
E)All of
Q8: Which of the following is true of
Q9: Heterotypic signaling between different cell types in
Q10: Blood vessels within tumors are
A)Often constructed in
Q11: Stromal cells formed within various types of
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