Which of the following scenarios will NOT result in an increase in apoptotic activity?
A)Overexpression of Noxa
B)Inhibition of Bcl-2 signaling
C)Phosphorylation of Bim
D)Activation of caspase-9
E)Flux in cellular calcium levels

Question

Quizplus · Accepted Answer

Phosphorylation of Bim often leads to its inactivation or degradation, which would not increase apoptotic activity but rather decrease it, as Bim is a pro-apoptotic BH3-only protein that promotes apoptosis when active.

Which of the Following Scenarios Will NOT Result in an Increase