Li-Fraumeni syndrome is linked to a greater risk of cancer as a result of the inheritance of a germline mutation in one copy of _____.

Question

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Li-Fraumeni syndrome is caused by the inheritance of a germline mutation in one copy of the p53 tumor suppressor gene, which is responsible for regulating cell growth and division. Mutations in p53 lead to an increased risk of developing various types of cancer, including breast cancer, bone cancer, and brain tumors.

Li-Fraumeni Syndrome Is Linked to a Greater Risk of Cancer