All of the following are characteristics of tissue transglutaminase except ____.
A) generation of negatively charged peptides that bind well to the positively charged pockets of the DQ2 and DQ8 allotypes
B) conversion of glutamine to glutamate by deamination
C) upregulation during tissue inflammation
D) stimulation of IgG or IgA autoantibodies in celiac disease
E) predisposition to celiac disease if individual possesses particular polymorphic variants.
Correct Answer:
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