Mutations Affecting All of the Following Except _____ Interfere Directly

Mutations affecting all of the following except _____ interfere directly with the rearrangement of immunoglobulin and T-cell receptor genes.

A) Artemis
B) purine nucleoside phosphorylase (PNP)
C) DNA-dependent protein kinase (DNA-PK)
D) RAG-1
E) RAG-2.