The disadvantage of having a longer hinge region in IgG3 compared with the other IgG subclasses is a reduction in its serum half-life because of its susceptibility to _____.
A) increased proteolysis by serum proteases
B) clearance by erythrocytes via FcR binding
C) immune complex formation and deposition in kidney glomeruli
D) complement fixation and uptake by cells bearing receptor CR1
E) opsonization by neutrophils.
Correct Answer:
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