Which of the Following Is a Feature of Regulatory T

Which of the following is a feature of regulatory T cells (T_reg) ? (Select all that apply.)

A) T_reg express CD8 and control effector cells by inducing apoptosis.
B) T_reg express high levels of CD25 (IL-2 receptor α chain) and secrete pro-inflammatory cytokines such as IFN-γ.
C) Physical association between T_reg and their target cells is mandatory for T_reg function.
D) By interacting with dendritic cells in secondary lymphoid tissue,T_reg prevent the interaction and activation of naive T cells.
E) T_reg secrete TGF-β and suppress effector T-cell function.