Expression of IFN-γ is induced in a CD4 T_H1 cell under the direction of the transcription factor ______.

Question

Quizplus · Accepted Answer

The transcription factor T-bet is known to induce the expression of IFN-γ in CD4 T cells. FoxP3 is a transcription factor involved in the development and function of regulatory T cells, and is not known to induce IFN-γ expression. AP-1 is a transcription factor important in immune cell activation, but its role in inducing IFN-γ expression in CD4 T cells is not as well-established as T-bet. GATA-3 is a transcription factor important for the development and function of Th2 cells, which typically do not produce IFN-γ. NFAT is a transcription factor involved in T cell activation and differentiation, but its role in inducing IFN-γ expression in CD4 T cells is not as well-established as T-bet.

Expression of IFN-γ Is Induced in a CD4 TH1 Cell

Expression of IFN-γ Is Induced in a CD4 T_H1 Cell