Which of the following characteristics permits activated CD8 T cells to destroy any cell type harboring viable and replicating pathogens such as viruses?

Question

Quizplus · Accepted Answer

CD8 T cells recognize pathogens through the interaction between their T cell receptors (TCRs) and pathogen-derived peptides presented on MHC class I molecules. MHC class I molecules are expressed on most nucleated cells, allowing CD8 T cells to detect and destroy any cell type that harbors viable and replicating pathogens. Option A is incorrect because CD8 T cells are not equipped to target extracellular pathogens. Option B is incorrect because CD8 T cells do not enable macrophages to kill intracellular pathogens; rather, they directly kill infected cells themselves. Option C is partially correct but incomplete; pathogen-derived peptides must be presented on MHC class I molecules, not endocytic vesicles. Option D is incorrect because MHC class II molecules are not involved in the recognition and destruction of infected cells by CD8 T cells.

Which of the Following Characteristics Permits Activated CD8 T Cells