A developing B cell unable to generate a productive rearrangement on any of the four light-chain loci will undergo

Question

Quizplus · Accepted Answer

If a developing B cell cannot generate a productive rearrangement on any of the four light-chain loci, it will not be able to produce a functional B cell receptor and therefore will trigger apoptosis, a programmed cell death. This is a mechanism to ensure that non-functional or self-reactive B cells are eliminated from the repertoire.

A Developing B Cell Unable to Generate a Productive Rearrangement