Peptides that bind to a particular MHC isoform usually have either the same or chemically similar amino acids at two to three key positions that hold the peptide tightly in the peptide-binding groove of the MHC molecule.These amino acids are called _____ and the combination of these key residues is known as its _____.

Question

Quizplus · Accepted Answer

The amino acids that hold the peptide tightly in the peptide-binding groove of the MHC molecule are called anchor residues, and the combination of these key residues is known as its peptide-binding motif.

Peptides That Bind to a Particular MHC Isoform Usually Have