The enzyme responsible for recombining V,D,and J segments during somatic recombination is called

Question

Quizplus · Accepted Answer

V(D)J recombinase is the correct answer because it is the specific enzyme responsible for recombining (and rearranging) the variable (V), diversity (D), and joining (J) segments during somatic recombination in B and T cells. Terminal deoxynucleotidyl transferase adds N nucleotides to the joining segments, exonuclease removes nucleotides, DNA polymerase synthesizes new DNA strands, and DNA ligase seals the breaks in the DNA backbone. However, none of these enzymes are specifically responsible for the recombination of V, D, and J segments.

The Enzyme Responsible for Recombining V,D,and J Segments During Somatic