The highest degree of diversity resulting from somatic recombination is concentrated ____________ of the VH and VL domains,whereas the point mutations caused by somatic hypermutation are found ____________.
A) in CDR3; throughout the V region
B) in CDR3; in CDR1 and CDR2 of VH and VL domains
C) in CDR1 and CDR2; in CDR3
D) in CDR1 and CDR2; throughout the V region
E) in all three CDRs; in C regions.
Correct Answer:
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