The process of _____ results in change in the constant region of the heavy-chain of antibodies,causing a change in the effector function and transport properties of antibodies:

Question

Quizplus · Accepted Answer

Isotype switching is the process by which a B cell changes the constant region of its heavy-chain gene, resulting in a different class of antibody being produced (e.g. IgM to IgG). This process alters the effector function and transport properties of the antibody. Complement fixation and neutralization involve different mechanisms for altering antibody function, while somatic hypermutation and somatic recombination do not involve changes in the constant region of the heavy chain.

The Process of _____ Results in Change in the Constant