Which immunoglobulin isotypes (out of IgM, IgG1, IgG2, IgG3, IgG4, IgA, IgE, and IgD) participate in (a) neutralization; (b) opsonization; (c) sensitization for killing by NK cells; (d) sensitization of mast cells; (e) activation of complement? Which isotypes (f) are transported across epithelium; (g) are transported across the placenta; (h) diffuse into extravascular sites?
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