Recent research finds that the risk of adverse outcomes in older adults is greater for SSRIs than with __________ and yet, with all factors considered, Canadian guidelines continue to recommend SSRIs as first line medication for depression in older adults.

Question

Quizplus · Accepted Answer

Tricyclic antidepressants (TCAs) are known to have a higher risk of adverse outcomes in older adults compared to SSRIs, due to their side effect profile, which includes anticholinergic effects and cardiovascular risks. Despite this, SSRIs are recommended as first-line treatment due to their more favorable safety profile.

Recent Research Finds That the Risk of Adverse Outcomes in Older