Conditions that produce acute kidney injury by directly acting on functioning kidney tissue are classified as intrarenal.The most common intrarenal condition is

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The most common intrarenal condition is ATN.This condition may occur after prolonged ischemia (prerenal),exposure to nephrotoxic substances,or a combination of these.Some patients have ATN after only several minutes of hypotension or hypovolemia,whereas others can tolerate hours of renal ischemia without having any apparent tubular damage.

Conditions That Produce Acute Kidney Injury by Directly Acting on Functioning