Lactulose is considered the first-line treatment for hepatic encephalopathy and works by

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Lactulose is considered the first-line treatment for hepatic encephalopathy.Lactulose creates an acidic environment in the bowel that causes the ammonia to leave the bloodstream and enter the colon.Ammonia is trapped in the bowel.Lactulose also has a laxative effect that allows for elimination of the ammonia.Lactulose is given orally or via a rectal enema.

Lactulose Is Considered the First-Line Treatment for Hepatic Encephalopathy and Works