Tissue damage from burn injury activates an inflammatory response that increases the patient's risk for

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The loss of skin as the primary barrier against microorganisms and activation of the inflammatory response cascades results in immunosuppression,placing the patient at an increased risk of infection.A systemic inflammatory response syndrome (SIRS)also increases the risk of acute kidney injury in the presence of poor tissue perfusion.Acute respiratory distress syndrome is also a potential complication,but the risk of infection is greater because of the loss of the skin barrier.Catecholamine release and gastrointestinal ischemia are the causes of stress ulcers.

Tissue Damage from Burn Injury Activates an Inflammatory Response That