The primary benefit of CRISPR- Cas over TALENs and ZFNs is _______ .

Question

Quizplus · Accepted Answer

The primary benefit of CRISPR-Cas over TALENs and ZFNs is the ability of Cas9 to bind engineered sgRNA, which allows for greater specificity in targeting the desired DNA sequence compared to the other genome editing techniques. The speed, cost, and specificity of the nuclease are also benefits, but the ability to use engineered sgRNA is the most significant advantage.

The Primary Benefit of CRISPR- Cas Over TALENs and ZFNs