A son is born with Kleinfelter's syndrome and hemophilia.His father was normal and his mother was a carrier for the recessive X- linked blood clotting disorder.What occurred in meiosis to produce this genetic outcome?
A)nondisjunction in either meiosis I or meiosis II of the mother
B)nondisjunction in meiosis II of the father
C)nondisjunction in meiosis II of the mother
D)nondisjunction in meiosis I of the father
E)nondisjunction in meiosis I of the mother

Question

Quizplus · Accepted Answer

The son has an extra X chromosome (from the mother) due to nondisjunction in meiosis II of the mother, resulting in Kleinfelter's syndrome. Additionally, he inherited his mother's X chromosome with the hemophilia allele, which is then expressed since he only has one X chromosome. The father's meiosis is not involved in the inheritance of X-linked traits, as he only contributes a Y chromosome to his son.

A Son Is Born with Kleinfelter's Syndrome and Hemophilia