What two terms apply to the fusion of cultured human and mouse cells that produces cell lines that are useful in assigning a gene to a particular human chromosome?
A)forward and reverse
B)lod score and pod score
C)positive and negative
D)single and double
E)heterokaryon and synkaryon

Question

Quizplus · Accepted Answer

The two terms that apply to the fusion of cultured human and mouse cells are "heterokaryon" and "synkaryon". Heterokaryon refers to the initial stage of the fusion where two nuclei are present in the same cell but have not yet fused together. Synkaryon then refers to the later stage where the two nuclei have fused together into a single nucleus. These fused cells are useful in assigning a gene to a particular human chromosome through techniques such as somatic cell hybridization. Choice A (forward and reverse) and choice C (positive and negative) do not apply to this process. Choice B (lod score and pod score) refers to statistical methods used in genetic linkage analysis, which is not relevant to this question. Choice D (single and double) does not accurately describe the process of fusion of cells.

What Two Terms Apply to the Fusion of Cultured Human