Methods for determining the linkage group and genetic map in humans involve which of the following?
A)twin spots and tetrad analysis
B)tetrad analysis and bromodeoxyuridine
C)chiasma-type and classical analyses
D)zygotene and pachytene DNA syntheses
E)DNA markers

Question

Quizplus · Accepted Answer

Methods for determining the linkage group and genetic map in humans typically involve the use of DNA markers, such as microsatellites or single nucleotide polymorphisms (SNPs). These markers can be tracked through families to determine their relative positions on chromosomes, allowing for the construction of a genetic map. Methods such as twin spots, tetrad analysis, and bromodeoxyuridine are typically used in model organisms such as yeasts and fruit flies, while chiasma-type and classical analyses refer to observations of meiotic recombination events and chromosome structure in a variety of organisms. Zygotene and pachytene refer to specific stages of meiotic prophase, which can be useful for studying chromosome behavior but are not typically used for constructing genetic maps.

Methods for Determining the Linkage Group and Genetic Map in Humans