Albinism is an autosomal recessive trait in humans.Assume that there are 100 albinos aa)in a population of 1 million.How many individuals would be expected to be homozygous normal AA under equilibrium conditions?
A)980,100
B)100
C)10,000
D)999,900
E)19,800

Question

Quizplus · Accepted Answer

Under Hardy-Weinberg equilibrium, the frequency of the recessive allele (a) can be calculated using the formula q^2 = number of aa individuals / total population. Given 100 aa individuals in a population of 1 million, q^2 = 100/1,000,000 = 0.0001, and q = sqrt(0.0001) = 0.01. The frequency of the dominant allele (A) is p = 1 - q = 0.99. The frequency of homozygous dominant individuals (AA) is p^2 = (0.99)^2 = 0.9801, or 98.01% of the population. Therefore, the expected number of AA individuals is 0.9801 * 1,000,000 = 980,100.

Albinism Is an Autosomal Recessive Trait in Humans