The gene p53 is called the _____because it corrects mutations in the spindle apparatus before nondisjunction can occur.

Question

The gene p53 is called the  _____because it corrects mutations in the spindle apparatus before nondisjunction can occur.

Quizplus · Accepted Answer

The gene p53 is commonly referred to as the "guardian of the genome" because it plays a critical role in preventing mutations and maintaining genomic stability. It acts as a tumor suppressor monitor by regulating cell cycle checkpoints and inducing either cell cycle arrest or apoptosis in response to DNA damage or other abnormalities. It primarily functions at the G1/S checkpoint but can also correct abnormalities in the spindle apparatus during the M phase checkpoint, which helps prevent nondisjunction and promotes accurate chromosome segregation during cell division.

The Gene P53 Is Called the _____Because It Corrects