About 5% of those with Rubinstein- Taybi syndrome develops cancer as a result to decreased gene expression.This is directly linked to abnormal histone modification caused by a dysfunctional enzyme.What enzyme is this?

Question

Quizplus · Accepted Answer

Histone acetyltransferase (HAT) is the enzyme linked to Rubinstein-Taybi syndrome through its role in histone modification. Mutations affecting HAT activity can lead to abnormal chromatin structure and gene expression, increasing cancer risk.

About 5% of Those with Rubinstein- Taybi Syndrome Develops Cancer