A long poly- A- tail is necessary to initiate translation.Which protein binds directly to eIF4E to inhibit translation initiation?
A)maskin
B)PABP
C)CPEB
D)PARN
E)poly- A polymerase

Question

Quizplus · Accepted Answer

Maskin binds directly to eIF4E to inhibit translation initiation, whereas PABP (poly-A binding protein) binds to the poly-A tail to enhance translation initiation. CPEB (cytoplasmic polyadenylation element binding protein) and PARN (poly-A specific ribonuclease) are involved in post-transcriptional regulation of mRNA stability and translation, while poly-A polymerase adds the poly-A tail to the 3' end of mRNA.

A Long Poly- A- Tail Is Necessary to Initiate Translation