Which of the following mutations would be classified as a transversion?

Question

Quizplus · Accepted Answer

A transversion is a point mutation that involves the substitution of a purine for a pyrimidine or vice versa. In this case, CGA (coding for arginine, a purine) to CGT (coding for arginine, a pyrimidine) is a substitution of a purine for a pyrimidine and therefore a transversion. The other options are all substitutions of one purine for another (Option A and D) or one pyrimidine for another (Option C) and are therefore classified as transitions. Option B is a substitution of a pyrimidine for a purine but, specifically, a substitution of guanine for adenine which would also be classified as a transversion, but it is not the best option since Option E is a more precise answer.

Which of the Following Mutations Would Be Classified as a Transversion