The hospitalized client has received an excessive dose of isoniazid.Which of the following drugs should the nurse ensure is available on the nursing unit for use as an antidote?

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Pyridoxine, also known as vitamin B6, is the antidote for an excessive dose of isoniazid. It helps to prevent or treat neurotoxicity caused by isoniazid overdose. The other options (A) glucagon, (C) leucovorin, and (D) naloxone are not used as antidotes for isoniazid overdose. Glucagon is used to treat hypoglycemia, leucovorin is used to treat methotrexate toxicity, and naloxone is used to reverse the effects of opioid drugs.

The Hospitalized Client Has Received an Excessive Dose of Isoniazid