A 79-year-old woman with type 2 diabetes has recently been placed on glipizide (Glucotrol)5 mg by mouth four times a day.She needs to receive instructions about which of the following drug interactions?

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Sodium warfarin (Coumadin) has a significant drug interaction with glipizide. Glipizide can increase the effects of warfarin, leading to an increased risk of bleeding. Therefore, the patient should be instructed to monitor for any signs of bleeding and to notify their healthcare provider if any occur. The other options (acetaminophen, tetracycline, and erythromycin) do not have significant drug interactions with glipizide.

A 79-Year-Old Woman with Type 2 Diabetes Has Recently Been