The nurse determines that which of the following drugs listed on the client's medication administration record poses the least risk of harmful interaction with spironolactone (Aldactone)?

Question

Quizplus · Accepted Answer

Ibuprofen (Motrin), a nonsteroidal anti-inflammatory drug (NSAID), poses the least risk of harmful interaction with spironolactone compared to the other options. Spironolactone is a potassium-sparing diuretic, and combining it with medications that increase potassium levels (like potassium chloride) or other drugs that affect kidney function and electrolyte balance (like ACE inhibitors such as lisinopril or medications affecting renal lithium clearance) can lead to significant adverse effects. NSAIDs like ibuprofen have a lower risk of interaction in this context.

The Nurse Determines That Which of the Following Drugs Listed