Lipophilic hormones must interact with which of the following prior to gene activation?
A) membrane receptors
B) G-proteins
C) intracellular receptors
D) adenylate cyclase
E) both intracellular receptors and adenylate cyclase

Question

Quizplus · Accepted Answer

Lipophilic hormones are able to penetrate the plasma membrane and bind to intracellular receptors, typically located in the cytoplasm or nucleus. This binding triggers a conformational change in the receptor, allowing it to interact with specific DNA sequences and activate gene transcription. Therefore, interaction with intracellular receptors is necessary for gene activation by lipophilic hormones. Membrane receptors, G-proteins, and adenylate cyclase are typically involved in signal transduction pathways for hydrophilic hormones.

Lipophilic Hormones Must Interact with Which of the Following Prior