Because of countercurrent multiplication, the loop of Henle is able to establish a vertical osmotic gradient in the renal medulla, ranging from 300 to 1,200 mosm/liter, despite the fact that the active salt pump of the ascending limb is only able to produce a 200 mOsm/liter osmotic gradient at each horizontal level.

Question

Quizplus · Accepted Answer

Countercurrent multiplication allows for the establishment of a vertical osmotic gradient in the renal medulla that ranges from 300 to 1,200 mosm/liter, which is greater than the 200 mOsm/liter osmotic gradient produced by the active salt pump of the ascending limb at each horizontal level.

Because of Countercurrent Multiplication, the Loop of Henle Is Able