The peripheral chemoreceptors are not activated during carbon monoxide poisoning despite the fact that the total O₂ content in the blood can become lethally low.

Question

Quizplus · Accepted Answer

Peripheral chemoreceptors respond to changes in the partial pressure of oxygen (PaO2), not the total oxygen content. In carbon monoxide poisoning, PaO2 remains normal, so these receptors are not activated.

The Peripheral Chemoreceptors Are Not Activated During Carbon Monoxide Poisoning