How did white settlers who traveled west in wagon trains during the mid-1800s bring devastation to the Plains Indians?

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White settlers who traveled west in wagon trains during the mid-1800s brought devastation to the Plains Indians by bringing with them alcohol and deadly diseases. The Indians had no immunity to these new diseases, and they spread rapidly through Indian communities, decimating their populations. Additionally, many white settlers viewed the Indians as obstacles to their westward expansion and attempted to kill them or force them off their land. However, while some white settlers did kill off great herds of deer and antelope, and there were instances of deliberate destruction of Indian farms, these factors were not the primary sources of devastation for the Plains Indians.

How Did White Settlers Who Traveled West in Wagon Trains