What is the main difference in the mechanism of action between topical anesthetics and injectable anesthetics?

Question

Quizplus · Accepted Answer

Topical anesthetics work by blocking nerve conduction at the site of application on the skin or mucous membranes. Injectable anesthetics, on the other hand, are administered directly into the tissues, blocking nerve conduction closer to the nerve fibers themselves. The main difference in mechanism of action is therefore the location of the blocking of nerve conduction.

What Is the Main Difference in the Mechanism of Action