What is the lipid solubility and the protein-binding ability of the local anesthetic related to?
A) Anesthetic dissociation constant
B) Anesthetic duration of action
C) Distribution of cations and anions
D) All options listed

Question

Quizplus · Accepted Answer

The lipid solubility and protein-binding ability of a local anesthetic are related to its duration of action. Higher lipid solubility and protein binding generally result in a longer duration of action.

What Is the Lipid Solubility and the Protein-Binding Ability of the Local