Which of the four processes involved in nociception uses mediators such as serotonin or histamine to create an action potential from noxious stimuli?

Question

Quizplus · Accepted Answer

Transduction is the process by which noxious stimuli are converted into electrical signals (action potentials) that can be transmitted by nerves to the brain. During transduction, mediators such as serotonin and histamine can bind to receptors on nociceptor fibers and trigger the opening of ion channels, allowing ions to flow into the nerve and create an action potential. The other processes of nociception (transmission, modulation, perception) do not involve the use of mediators to create action potentials.

Which of the Four Processes Involved in Nociception Uses Mediators