One effect of drug misuse is changes in brain circuits. This leads to

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Drug misuse can lead to changes in brain circuits, which can result in strong cravings when exposed to people, places or things that trigger memories of drug use. This can make it difficult for individuals to sustain their recovery and avoid relapse. Loss of REM sleep, a split between different levels of consciousness, and narcolepsy are not typically associated effects of drug misuse on the brain circuits.

One Effect of Drug Misuse Is Changes in Brain Circuits