Which one of the following x-linked disorders is caused by an abnormal number of repeat sequences in the genome and is the most common cause of inherited mental impairment?
A) fragile X syndrome
B) Klinefelter syndrome
C) Williams syndrome
D) cri du chat syndrome
E) Down syndrome

Question

Quizplus · Accepted Answer

Fragile X syndrome is caused by an abnormal number of CGG repeat sequences in the FMR1 gene on the X chromosome, leading to the silencing of the gene and a deficiency in the protein it codes for, which is important for neural development and function. It is the most common cause of inherited intellectual disability, affecting approximately 1 in 4000 males and 1 in 8000 females.

Which One of the Following X-Linked Disorders Is Caused by an Abnormal