One side effect of anabolic steroids to increase muscle bulk is that the testes shrink. Since the testes also produce testosterone, what is the likely mechanism for this shrinkage?
A) The anterior pituitary assumes overproduction and drops the level of hormones that cause the testes to develop.
B) Artificial testosterone causes a negative feedback to the anterior pituitary that in turn tries to stimulate ovary development.
C) Testosterone has a negative feedback effect directly on testes.
D) Artificial testosterone is toxic to testicular cells.
E) Excess testosterone actually backfires and reverses the effects of puberty.

Question

Quizplus · Accepted Answer

The anterior pituitary senses the high levels of artificial testosterone and reduces the secretion of hormones like LH (Luteinizing Hormone) and FSH (Follicle Stimulating Hormone) that stimulate the testes to produce testosterone and sperm, leading to testicular shrinkage.

One Side Effect of Anabolic Steroids to Increase Muscle Bulk