Which antibody class is most responsible for the allergic reaction?
A) IgA
B) IgD
C) IgE
D) IgG
E) IgM

Question

Quizplus · Accepted Answer

IgE is the antibody class most responsible for the allergic reaction. When an allergen enters the body, it triggers the production of IgE antibodies which bind to mast cells and basophils. Upon re-exposure to the allergen, the IgE antibodies on these cells bind to the allergen, causing the release of histamine and other inflammatory mediators, leading to the symptoms of an allergic reaction.

Which Antibody Class Is Most Responsible for the Allergic Reaction