Which of the following best defines substrate-level ATP synthesis?
A) An enzyme passes a high-energy phosphate to ADP, resulting in ATP.
B) ATP is used to activate glucose for glycolysis.
C) An exergonic reaction is used to drive the synthesis of ATP from ADP plus phosphate.
D) Oxidation of a substrate results in a high-energy bond.
E) ATP is synthesized from adenosine plus three phosphates.

Question

Quizplus · Accepted Answer

Substrate-level ATP synthesis occurs when an enzyme directly passes a high-energy phosphate from a substrate to ADP, resulting in the synthesis of ATP. This occurs during glycolysis and the Krebs cycle in cellular respiration. Option B refers to the activation of glucose, not ATP synthesis. Option C describes oxidative phosphorylation, not substrate-level ATP synthesis. Option D describes a type of reaction that can occur during cellular respiration, but it does not specifically refer to substrate-level ATP synthesis. Option E is incorrect because adenosine is not involved in substrate-level ATP synthesis.

Which of the Following Best Defines Substrate-Level ATP Synthesis