If we developed a molecule that blocked the ATP channel protein, what would be the first immediate effect?
A) accumulation of ATP in the mitochondrial matrix
B) accumulation of NADH in the mitochondrial matrix
C) no energy to pump hydrogen ions into the intermembrane space of a mitochondrion
D) reversal of the hydrogen ion gradient
E) immediate blockage of the cytochrome molecules

Question

Quizplus · Accepted Answer

Blocking the ATP channel protein would prevent ATP from being transported out of the mitochondrial matrix, leading to its accumulation within the matrix. This is because the ATP synthase channel is responsible for allowing ATP, which is generated in the matrix via the electron transport chain and chemiosmosis, to exit into the cytoplasm where it can be used by the cell. Blocking this channel would not directly affect the other processes mentioned, such as NADH accumulation, hydrogen ion pumping, the hydrogen ion gradient, or the function of cytochrome molecules in the electron transport chain.

If We Developed a Molecule That Blocked the ATP Channel