Microtubule-organizing centers will begin to migrate toward the cell poles during:

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During prophase, microtubule-organizing centers, known as centrosomes, will begin to migrate toward the cell poles. This is the first step in forming the mitotic spindle, which is necessary for successful cell division. During metaphase, the spindle is fully formed and the chromosomes align at the equator. During anaphase, the sister chromatids are separated and pulled to opposite poles by the spindle fibers. During telophase, the nuclear envelope reforms and the cell prepares to divide into two daughter cells.

Microtubule-Organizing Centers Will Begin to Migrate Toward the Cell Poles